Journal article

Current challenges in the practice of epilepsy surgery

JM Wrench, R Matsumoto, Y Inoue, SJ Wilson

Epilepsy and Behavior | Published : 2011

Abstract

The accurate prediction of individual outcomes after epilepsy surgery represents a key challenge facing clinicians. It requires a precise understanding of surgical candidacy and the optimal timing of surgery to maximize a range of outcomes, including medical, psychosocial, cognitive, and psychiatric outcomes. We promote careful consideration of how epilepsy has affected an individual's developmental trajectory as key to constructing more differentiated profiles of postsurgical risk or resilience across multiple outcome measures. This life span approach conceives surgery as a crucial "turning point" in an individual's development from which varied outcome trajectories may follow. This helps c..

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University of Melbourne Researchers

Grants

Awarded by Cleveland Clinic Foundation


Funding Acknowledgements

Studies reported by Wrench and Wilson were partly supported by an Australian Research Council Linkage Project Award (LP0453690). These authors thank Kylie Barker and Sophia Halley for collecting some of the voxel-based morphometry data. Studies reported by Matsumoto and colleagues were partly supported by the Advanced International Clinical Fellowship Award from the Cleveland Clinic Foundation; Grants-in-Aid for Young Scientists (B) 17790578 and Scientific Research (C) 20591022 from the Japan Ministry of Education, Culture, Sports, Science and Technology (MEXT); and research grants from the Japan Epilepsy Research Foundation and Kanae Foundation for Life and Sociomedical Science.